Specialized AI agents built from curated domain skills can meaningfully augment expert decision-making in high-stakes clinical work, achieving better results than general LLMs by combining retrieval, orchestration, and executable tools.
ClinGeX is an AI agent that helps clinical genomicists analyze patient DNA sequences by orchestrating 105 specialized skills to interpret genetic variants and guide treatment decisions. In tests with real cases and clinical experts, it achieved 71.7% accuracy compared to 45.7% for competing systems, and significantly improved expert performance when used collaboratively.