Agentic systems that combine structured experimental evidence with tool use can dramatically improve drug formulation discovery—Andromeda 2 achieved 3x better results than the previous probabilistic model by leveraging in-house data to guide autonomous lab experiments.
Andromeda 2 is an AI agent that designs drug formulations by reasoning over experimental data and using lab tools to test batches automatically. It outperformed traditional optimization and manual design methods at finding high-performing formulations for paclitaxel, a poorly soluble drug, achieving 50% success versus 17% and 2% for competing approaches.